An extensive family collection, the Vaux Family Papers center around the lives of George Vaux V (1721-1803), George Vaux VII (1779-1836), and George Vaux VIII (1832-1915), their business partners, siblings, wives, and children, and encompasses the extended Vaux family of Warders, Sansoms, Heads, Graffs, Morrises, Cressons, and Mayberrys. The collection includes correspondence, financial accounts, receipts, business records, journals, diaries, photographs, and legal documents.

This collection contains mostly entomological material, with much information on the description and identification of particular insects, entomological collections, and the study of entomology in Europe and the United States. In addition, there are materials on medicine and hospitals during the American Civil War, on the Corps of Topographical Engineers, the United States Army, on natural history in the United States, and on the LeConte's family. Some letters are written to President Rutherford B. Hayes and concern the Commissionership of Agriculture, for which LeConte was considered, but not appointed. Letters of John Eatton LeConte and Joseph LeConte are included.

The Peale family is best known as a family of artists; however, family interests and activities were much more wide-ranging. The best known Peale is Charles Willson Peale (1741-1827, APS 1786), who produced more than one thousand paintings, including hundreds of portraits of leading Americans during the colonial and early national periods. Peale was married three times, to Rachel Brewster (1744-1790), Elizabeth de Peyster (1765-1804), and Hannah More (1755-1821). He had eighteen children, eleven of whom reached adulthood. Three of Charles Willson Peale's sons became artists: Raphaelle Peale (1774-1825), Rembrandt Peale (1778-1860), and Rubens Peale (1784-1865). A fourth son, Titian Ramsay Peale (1799-1885, APS 1833), was a naturalist (who made drawings on the exploring expeditions he accompanied) and pioneer in photography, and another son, Benjamin Franklin Peale (1795-1870), became a naturalist and paleontologist. Peale's daughter Sophonisba Angusciola was married to Coleman Sellers (1781-1834), an inventor and manufacturer of machinery, including locomotives. Two of their sons, George Escol Sellers (1808-1899) and Coleman Sellers (1827-1907, APS 1872), were inventors and engineers. The latter served as director of the construction of the hydro-electric power development at Niagara Falls. He was married to Cornelia Wells Sellers (1831-1909). One of their grandsons was Charles Coleman Sellers (1903-1980, APS 1979), a librarian and historian and the author of several studies of the Peale family, including a Charles Willson Peale biography.

The collection of about 850 items covers the period from 1782 to c. 1936, with the bulk dating to the 1780s to 1840s. The collection is divided into four series. Series I contains correspondence relating to a wide variety of topics, including French and English politics, business, trade, religious matters, and personal affairs. Many of the items are letters of introduction. There is also information on John Vaughan's immigration to America, Joseph Priestley, vaccines and inoculation (with Jefferson's comments on the same), Vaughan's business in Philadelphia, and the American Philosophical Society. Also included in this series are 2 boxes with copies of Vaughan correspondence as well as miscellaneous notes by E. W. Madeira, gathered in the course of his research on Vaughan in the 1930s. Series II consists of three volumes. Included are two of Vaughan's commonplace books. One, entitled, "J. Vaughan's book," May 17, 1779 (47 pp., in Latin; 870/L34), includes mostly Latin notations. The other commonplace book, dated 1783 (ca. 66 pp.; B V 462.c), includes comments on several prominent Americans, such as Benjamin Rush and David Rittenhouse, as well as American society generally. The third volume is a copybook with thirty letters spanning the period 1784 to 1801 (B V462.1). Series III includes material relating to Vaughan's administration of the estate of the Philadelphia merchant Samuel Merrick, 1796-1822 (Vaughan-Merrick Papers, B V462.m; 2 boxes). Series IV consists of correspondence between Vaughan and the DuPont Co. for which he served as agent (B V462.4; photocopies of 73 letters).

A leading national opinion maker and influential regional politician, tied by marriage to the families of Benjamin Franklin and cognate families, William Duane (1760-1835) played key roles in the field of political journalism, as well as national, Pennsylvania and local Philadelphia politics. Editor of the Aurora, William Duane (1760-1835) assured himself gratitude from Jefferson and the Republicans and enmity from President Adams and the Federalists for his open and effective attacks on Federalist policies. His son William John Duane (1780-1865), was a prominent member of the Pennsylvania legislature, a legal advisor to Stephen Girard, Solicitor for many of Philadelphia's premier institutions, and Secretary of the Treasury of the United States (June-September 1833). The Duane Family Collection contains a diverse assemblage of personal and professional correspondence relating to family members, with interesting material relating to William Duane (1760-1835), his son, William John Duane (1780-1865), grandson William Duane (1808-1882), great-grandson Charles Williams Duane (1837-1915), and other relations. The collection includes unique correspondence from and relating to Benjamin Franklin's family, as well as correspondence with Thomas Jefferson and other leading figures from the early nineteenth century. The collection also includes prints, photographs of family members, as well as some maps.

The son of William Franklin, Royal Governor of New Jersey, William Temple Franklin worked as aide to his grandfather, Benjamin Franklin, when the latter served as minister to France during the American Revolution. A bonvivant, Temple received his highest public appointment as Secretary to the American delegation at the Treaty of Versailles in 1782-1783, largely through the influence of his famous grandfather, but never again attained a significant post. As Franklin's literary heir, he edited and published a three volume set of his grandfather's writings in 1817. He married his long time mistress a few months before his death in Paris in 1823. The William Temple Franklin Papers provides a richly detailed portrait of the life of the grandson of Benjamin Franklin, and consists largely of letters received during the years that Temple served as his grandfather's aide in France, 1776-1785. Although much of the correspondence is routine, during this period, Temple received regular reports from friends and diplomatic colleagues relaying information on the American Revolution, the course of diplomatic and peace negotiations, and French public opinion on Benjamin Franklin and the new United States. The collection is also a rich resource for information on the personal lives of the Franklins, including interesting correspondence from Temple's relatives William Franklin, Elizabeth Franklin, Sarah Franklin Bache, and Jonathan Williams, and his mistress Blanchette Caillot.

A collection of letters, legal papers and financial records of three generations of the prominent Philadelphia family. Spanning 1745-1955, detailed are the legal cases and political advocacy work of John Kintzing Kane (1795-1858), Robert Patterson Kane (1827-1906), and Francis Fisher Kane (1866-1955). Also includes correspondence, architectural drawings, and photograph albums of the Cope family. Robert Patterson Kane's daughter Eliza Middleton Kane (1863-1952) married the Philadelphia architect Walter Cope (1860-1902) in 1893. The APS papers of Elisha Kent Kane are in call no. B K132.

James Burd (1726-1793) was well-known in colonial Pennsylvania through his role in the French and Indian War, as well as his connections to many of the colony's leading families (most notably the Shippen family). Initially starting out as a merchant in Philadelphia, Burd became increasingly involved with colonial affairs after moving to Lancaster County with his family in 1752. It would be on the frontier where Burd would make his mark first as a soldier, and later as a magistrate. The Burd-Shippen Papers consist mainly of letters and business documents sent to James Burd, with the bulk of the collection relating to the French and Indian War, 1754-1763, in which Burd served as an officer commanding troops at Fort Augusta and elsewhere. The collection reflects all aspects of Burd's life in Pennsylvania as a merchant, soldier, and magistrate; as well as his involvement with the Shippen family professionally and personally. Intermixed with items sent to Burd are receipts to his wife Sarah Shippen Burd, and correspondence between Edward Shippen and James Hamilton regarding land matters and Indian affairs in Lancaster.

This is a collection of letters, letterbooks, account books, scrapbooks, etc., concerning the families of Robert Hare and Thomas Willing. The letters and other documents include early family material, as well as documents written by numerous family relations, and some obviously only collected by them. The Willing family letters (1744-1901) are diverse, concerning family matters, business, society, comments on the Civil War, etc. There are numerous letters from Thomas Willing, many concerning his banking career, as President of the Bank of North America and later at the first Bank of the U.S. The Hare family letters (1724-1965) are more extensive and diverse, including much on travel in the U.S. and elsewhere. There is a letter from Robert Hare Jr. concerning steam engines, and letters from Horace Binney Hare concerning his education at Harvard, 1860, his trip to San Francisco and the west, 1862, and numerous letters written while a soldier in the Civil War. There are many letters from Horace Binney (1780-1875, DAB) to his daughter Esther, who was married to John Innes Clark Hare (1816-1905, DAB), concerning family travel and court cases. There are also letters from outside the family, such as those from Dorothea L. Dix. The bound volumes include, among others: Robert Hare letterbooks (1824-1825, 1841-1857), estate records, and laboratory expense accounts (1818-1860); G. H. Hare's journal or log of cruises aboard the U.S. United States (1841) and U.S. Flint (1845); Horace Binney Hare's 1862 journal of his trip to San Francisco. There are account books and accounts (1754-1795) kept by Thomas Willing; accounts of the controversy over the estate of John Innes Clark; and records of the First Colored Wesley Methodist Church of Philadelphia (receipt book, 1820-1848; minute book, 1827-1844). There are also Philadelphia court records, and minutes of the Common Council of the city, 1832.

After a brief career in the Congregational church, J. Peter Lesley (1819-1903) left the ministry in 1852 to work full-time as a geologist. Having gained experience in structural geology and stratigraphy with the First Pennsylvania Geological Survey (1836-1842), Lesley became an expert in the geology of coal, working for the Pennsylvania Railroad and other corporations and conducting some of the first systematic studies of the state's hydrocarbon resources. A long-time professor at the University of Pennsylvania, he was elected to the APS in 1856, serving variously as its librarian, secretary, and vice president, and he was selected as Director of the Second Pennsylvania Geological Survey (1875-1889). The Lesley Papers include letters to and from Peter Lesley and his wife, Susan on geology, coal and iron mining, abolition, educational reform, organized charity, and Unitarianism. The collection offers important insight into academic and applied geology in late 19th century Pennsylvania, the development of the coal and iron industries, as well as into the Lesleys' progressive social and intellectual milieu. It is divided into three series: Lesley's general correspondence, his correspondence with his brother Joseph, and microfilms of Lesley's research notes.

This rich collection of letters and documents, which was assembled by Sol Feinstone (1888-1980) over a period of fifty years, includes material on almost all notable Americans from before the Revolution to the 1850's, as well as prominent Europeans, and there are documents relating to military affairs. There are substantial groups of letters from: John Adams, Henry Dearborn, Alexander Hamilton, Jedediah Huntington, Thomas Jefferson, Lafayette, George Washington, and a long run of letters from a Massachusetts military surgeon named Samuel Adams. Many letters, though written by Revolutionary figures, relate to events that occurred before or after the War.